Our Goal is to Understand the Mechanisms of Brain Restoration and Recovery
— - Sonia Villapol, Ph.D.

Peer-Reviewed Articles

  Citations: 920    h-index: 20    i10-index: 25

Citations: 920

h-index: 20

i10-index: 25

 
  • 2018

Traumatic brain injury in mice induces acute bacterial dysbiosis within the fecal microbiome.

Treangen TJ., Wagner J, Burns MP., Villapol S. Frontiers in Immunology, 9:2757. doi.org/10.3389/fimmu.2018.02757

 

Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.

Main BS, Villapol S, Sloley SS, Barton DJ, Parsadanian M, Agbaegbu C, Stefos K, McCann MS, Washington PM, Rodriguez OC, Burns MP. Mol Neurodegener. 2018 Apr 4;13(1):17. doi: 10.1186/s13024-018-0249-5. PMID:29618365

Proteolytic Remodeling of Perineuronal Nets: Effects on Synaptic Plasticity and Neuronal Population Dynamics.

Lorenzo Bozzelli P, Alaiyed S, Kim E, Villapol S, Conant K. Neural Plast. 2018 Feb 4;2018:5735789. doi: 10.1155/2018/5735789. eCollection 2018. Review. PMID: 29531525

 

Glial- and Neuronal-Specific Expression of CCL5 mRNA in the Rat Brain.

Lanfranco MF, Mocchetti I, Burns MP, Villapol S. Front Neuroanat. 2018 Jan 12;11:137. doi: 10.3389/fnana.2017.00137. eCollection 2017.PMID: 29375328

 

Roles of Peroxisome Proliferator-Activated Receptor Gamma on Brain and Peripheral Inflammation.

Villapol S. Cell Mol Neurobiol. 2018 Jan;38(1):121-132. doi: 10.1007/s10571-017-0554-5. Epub 2017 Oct 3. Review. PMID:28975471

 

  • 2017

Combination of Fluorescent in situ Hybridization (FISH) and Immunofluorescence Imaging for Detection of Cytokine Expression in Microglia/Macrophage Cells.

Fe Lanfranco M, Loane DJ, Mocchetti I, Burns MP, Villapol S. Bio Protoc. 2017 Nov 20;7(22). pii: e2608. doi: 10.21769/BioProtoc.2608. PMID:29238736

 

Temporal Changes in Cortical and Hippocampal Expression of Genes Important for Brain Glucose Metabolism Following Controlled Cortical Impact Injury in Mice.

Zhou J, Burns MP, Huynh L, Villapol S, Taub DD, Saavedra JM, Blackman MR. Front Endocrinol (Lausanne). 2017 Sep 11;8:231. doi: 10.3389/fendo.2017.00231. eCollection 2017. PMID:28955302

 

Sexual dimorphism in the inflammatory response to traumatic brain injury.

Villapol S, Loane DJ, Burns MP. Glia. 2017 Sep;65(9):1423-1438. doi: 10.1002/glia.23171. Epub 2017 Jun 13. PMID: 28608978

 

Reduced cortical excitatory synapse number in APOE4 mice is associated with increased calcineurin activity.

Neustadtl AL, Winston CN, Parsadanian M, Main BS, Villapol S, Burns MP. Neuroreport. 2017 Jul 5;28(10):618-624. doi: 10.1097/WNR.0000000000000811. PMID: 28542068

 

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury.

Main BS, Sloley SS, Villapol S, Zapple DN, Burns MP. J Vis Exp. 2017 Jun 20;(124). doi: 10.3791/55713. PMID: 28654066

 

NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury.

Barrett JP, Henry RJ, Villapol S, Stoica BA, Kumar A, Burns MP, Faden AI, Loane DJ. J Neuroinflammation. 2017 Mar 24;14(1):65. doi: 10.1186/s12974-017-0843-4. PMID:28340575

 

Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.

De Magalhaes Filho CD, Kappeler L, Dupont J, Solinc J, Villapol S, Denis C, Nosten-Bertrand M, Billard JM, Blaise A, Tronche F, Giros B, Charriaut-Marlangue C, Aïd S, Le Bouc Y, Holzenberger M. J Cereb Blood Flow Metab. 2017 Feb;37(2):396-412. doi: 10.1177/0271678X15626718. Epub 2016 Jul 20. PMID:26762506

 

  • 2016

Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1.

Allen M, Ghosh S, Ahern GP, Villapol S, Maguire-Zeiss KA, Conant K. Sci Rep. 2016 Oct 20;6:35497. doi: 10.1038/srep35497. PMID:27762280

 

Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma.

Winston CN, Noël A, Neustadtl A, Parsadanian M, Barton DJ, Chellappa D, Wilkins TE, Alikhani AD, Zapple DN, Villapol S, Planel E, Burns MP. Am J Pathol. 2016 Mar;186(3):552-67. doi: 10.1016/j.ajpath.2015.11.006. Epub 2016 Feb 5. PMID:26857506

 

Consequences of hepatic damage after traumatic brain injury: current outlook and potential therapeutic targets.

Villapol S. Neural Regen Res. 2016 Feb;11(2):226-7. doi: 10.4103/1673-5374.177720. No abstract available. PMID:27073366

 

Polypathology and dementia after brain trauma: Does brain injury trigger distinct neurodegenerative diseases, or should they be classified together as traumatic encephalopathy?

Washington PM, Villapol S, Burns MP. Exp Neurol. 2016 Jan;275 Pt 3:381-388. doi: 10.1016/j.expneurol.2015.06.015. Epub 2015 Jun 16. Review. PMID:26091850

 

  • 2015

Neurorestoration after traumatic brain injury through angiotensin II receptor blockage.

Villapol S, Balarezo MG, Affram K, Saavedra JM, Symes AJ. Brain. 2015 Nov;138(Pt 11):3299-315. doi: 10.1093/brain/awv172. Epub 2015 Jun 26. PMID:26115674

 

Hepatic expression of serum amyloid A1 is induced by traumatic brain injury and modulated by telmisartan.

Villapol S, Kryndushkin D, Balarezo MG, Campbell AM, Saavedra JM, Shewmaker FP, Symes AJ. Am J Pathol. 2015 Oct;185(10):2641-52. doi: 10.1016/j.ajpath.2015.06.016. PMID: 26435412

Neuroprotective effects of angiotensin receptor blockers.

Villapol S, Saavedra JM. Am J Hypertens. 2015 Mar;28(3):289-99. doi: 10.1093/ajh/hpu197. Epub 2014 Oct 31. Review. PMID: 25362113

 

  • 2014

Temporal dynamics of cerebral blood flow, cortical damage, apoptosis, astrocyte-vasculature interaction and astrogliosis in the pericontusional region after traumatic brain injury.

Villapol S, Byrnes KR, Symes AJ. Front Neurol. 2014 Jun 4;5:82. doi: 10.3389/fneur.2014.00082. eCollection 2014. PMID: 24926283

 

Temporal patterns of cortical proliferation of glial cell populations after traumatic brain injury in mice.

Susarla BT, Villapol S, Yi JH, Geller HM, Symes AJ. ASN Neuro. 2014 May 8;6(3):159-70. doi: 10.1042/AN20130034. PMID:24670035

 

  • 2013

 

Smad3 deficiency increases cortical and hippocampal neuronal loss following traumatic brain injury.

Villapol S, Wang Y, Adams M, Symes AJ. Exp Neurol. 2013 Dec;250:353-65. doi: 10.1016/j.expneurol.2013.10.008. Epub 2013 Oct 9. PMID: 24120438

 

Commercially available angiotensin II At₂ receptor antibodies are nonspecific.

Hafko R, Villapol S, Nostramo R, Symes A, Sabban EL, Inagami T, Saavedra JM. PLoS One. 2013 Jul 1;8(7):e69234. doi: 10.1371/journal.pone.0069234. Print 2013. PMID: 23840911

 

TGF-β superfamily gene expression and induction of the Runx1 transcription factor in adult neurogenic regions after brain injury.

Logan TT, Villapol S, Symes AJ. PLoS One. 2013;8(3):e59250. doi: 10.1371/journal.pone.0059250. Epub 2013 Mar 21. PMID:23555640

 

  • 2012

 

Inhaled nitric oxide reduces brain damage by collateral recruitment in a neonatal stroke model.

Charriaut-Marlangue C, Bonnin P, Gharib A, Leger PL, Villapol S, Pocard M, Gressens P, Renolleau S, Baud O. Stroke. 2012 Nov;43(11):3078-84. doi: 10.1161/STROKEAHA.112.664243. Epub 2012 Sep 4. PMID:22949477

 

Candesartan, an angiotensin II AT₁-receptor blocker and PPAR-γ agonist, reduces lesion volume and improves motor and memory function after traumatic brain injury in mice.

Villapol S, Yaszemski AK, Logan TT, Sánchez-Lemus E, Saavedra JM, Symes AJ. Neuropsychopharmacology. 2012 Dec;37(13):2817-29. doi: 10.1038/npp.2012.152. Epub 2012 Aug 15. PMID:22892395

 

Dual action of NO synthases on blood flow and infarct volume consecutive to neonatal focal cerebral ischemia.

Bonnin P, Leger PL, Villapol S, Deroide N, Gressens P, Pocard M, Renolleau S, Baud O, Charriaut-Marlangue C. Exp Neurol. 2012 Jul;236(1):50-7. doi: 10.1016/j.expneurol.2012.04.001. Epub 2012 Apr 12. PMID:22531298

 


  • 2011 - 2006

Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke.

Villapol S, Fau S, Renolleau S, Biran V, Charriaut-Marlangue C, Baud O. Pediatr Res. 2011 Jan;69(1):51-5. doi: 10.1203/PDR.0b013e3181fcb40b. PMID:20856166

 

Unilateral blood flow decrease induces bilateral and symmetric responses in the immature brain.

Villapol S, Bonnin P, Fau S, Baud O, Renolleau S, Charriaut-Marlangue C. Am J Pathol. 2009 Nov;175(5):2111-20. doi: 10.2353/ajpath.2009.090257. Epub 2009 Oct 8. PMID:19815715

 

Astrocytic demise in the developing rat and human brain after hypoxic-ischemic damage.

Gelot A, Villapol S, Billette de Villemeur T, Renolleau S, Charriaut-Marlangue C. Dev Neurosci. 2009;31(5):459-70. doi: 10.1159/000232564. Epub 2009 Aug 11. PMID: 19672074

 

Astrocyte responses after neonatal ischemia: the yin and the yang.

Villapol S, Gelot A, Renolleau S, Charriaut-Marlangue C. Neuroscientist. 2008 Aug;14(4):339-44. doi: 10.1177/1073858408316003. Epub 2008 Jul 8. Review. PMID: 18612085

 

Survivin and heat shock protein 25/27 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain.

Villapol S, Acarin L, Faiz M, Castellano B, Gonzalez B. Neuroscience. 2008 Apr 22;153(1):108-19. doi: 10.1016/j.neuroscience.2008.01.054. Epub 2008 Feb 14. PMID: 18358624

 

Distinct spatial and temporal activation of caspase pathways in neurons and glial cells after excitotoxic damage to the immature rat brain.

Villapol S, Acarin L, Faiz M, Castellano B, Gonzalez B. J Neurosci Res. 2007 Dec;85(16):3545-56. PMID:17668855

 

 Bilateral changes after neonatal ischemia in the P7 rat brain. 

Spiegler M, Villapol S, Biran V, Goyenvalle C, Mariani J, Renolleau S, Charriaut-Marlangue C. J Neuropathol Exp Neurol. 2007 Jun;66(6):481-90. Erratum in: J Neuropathol Exp Neurol. 2007 Jul;66(7):673. PMID: 17549008

 

Caspase-3 activation in astrocytes following postnatal excitotoxic damage correlates with cytoskeletal remodeling but not with cell death or proliferation.

Acarin L, Villapol S, Faiz M, Rohn TT, Castellano B, González B. Glia. 2007 Jul;55(9):954-65. PMID:17487878

 

Antioxidant Cu/Zn SOD: expression in postnatal brain progenitor cells.

Faiz M, Acarin L, Peluffo H, Villapol S, Castellano B, González B. Neurosci Lett. 2006 Jun 19;401(1-2):71-6. Epub 2006 Mar 29. PMID: 16567040